Waters nanoAcquity UPLC system

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Waters nanoAcquity UPLC system

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Waters nanoAcquity UPLC system includes

Waters nanoAcquity UPLC system features

The system consists of these modules and components:

- Binary solvent manager with flow control modules
The nanoACQUITY binary solvent manager is a high-pressure pump that moves solvent through the system. It provides steady (pulse-free) solvent flow at flow rates ranging from 0.20 to 5.00 μL/min (under closed loop control) or to 100.0 μL/min (under open loop control) at 69,000 kPa (690 bar, 10,000 psi). The solvent manager can generate high-pressure gradients with minimal gradient delay.

- Optional Binary solvent manager for 2D LC applications
Pump same as Binary solvent manager.

- Optional Auxiliary solvent manager
The nanoACQUITY auxiliary solvent manager incorporates two isocratic, high-pressure pumps that move solvent through the system and provide steady (pulse-free) solvent flow. Pump A is for sample loading. Pump B is for NanoLockSpray lock-mass addition, two-pump trapping, and 2D online separation. In the NanoLockSpray lock-mass addition mode, the pump operates at flow rates from 0.10 to 5.00 μL/min.

- Sample manager
The sample manager injects the samples it draws from microtiter plates, or vials, into the chromatographic flow stream. In maximum throughput mode, the sample manager can perform an injection in approximately 45 seconds, including a single default wash, or it can do so in less than 60 seconds, including a dual default wash. The sample manager accepts standard footprint plates, 5.03 ±0.02 inch × 3.365 ±0.02 inch, that conform to SBS/ANSI-compliant plates (maximum height of 2.2 inches, including covers). You may program any combination of plates and vial holders for automated sample processing. Samples are loaded into the sample manager via the front door. The sample manager can maintain samples at any temperature between 4 and 40 °C (39 and 104 °F) in ambient conditions of 25 °C (77 °F) or less.

- nanoACQUITY UPLC Console, which provides control, status, and advanced diagnostic information in a graphical display



Waters detailed information

The Waters® nanoACQUITY UPLC™ system is designed for capillary- to nano-scale separations and can perform simple chromatography up to 2D nanoLC. Its sensitivity, resolution, and reproducibility well suit it for biomarker discovery and proteomics applications, including protein identification and characterization.

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